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Purpose: The aim of this article is to study the feasibility of a delayed adjustable technique of strabismus surgery in children using an optional adjustable suture technique. Methods: The retrospective study included patients <12 years of age. Recessions were done using an optional adjustable bow-tie technique and resections were done by the conventional technique. Patients were evaluated on the third postoperative day and adjustments done when needed. Statistical analysis was done using Microsoft Excel 2010�. Results: The study included 11 patients with exotropia and 16 patients with esotropia. The mean age of the patients was 5.2 years (range 1� years). The mean preoperative distance deviation was 46.7 � 10.4 prism diopters (PD) for exotropic patients and 47.1 � 16.9 PD for esotropic patients. The mean preoperative near deviation was 46.6 � 11 PD for exotropic patients and 52.4 � 17.1 PD for esotropia. Two patients with exotropia (18.2%) and four patients with esotropia (25%) were adjusted under intravenous ketamine in the operating room under anesthetist supervision. No difficulty was encountered in advancing/recessing the muscles. The success rate at 1 month was 100% for exotropia and 87.5% for esotropia. The success rate at the final follow-up was 81.8% for patients with exotropia and 68.7% for patients with esotropia. Conclusions: This delayed optional adjustable strabismus surgery technique provides good short-term results and lower adjustment rates.
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Abstracts: Background & Aim: Accidental Poisoning in children focuses on the effect of substances caused by accidental poisonings from drugs of abuse, household products, or various other chemicals. Aim is to analyze children with accidental poisoning for the epidemiological factors; type of poison, time elapsed to reach the hospital, mode of poisoning, socioeconomic status and outcome. Methodology: This was a hospital based prospective observational study carried out at department of pediatrics, SVRR Government General Hospital during the periods of November 2011 to October 2013 . Total of 127 children admitted in the hospital were studied. Results: Most common cause of poisoning in children was kerosene (37.8%) followed by organophosphates(24.4%). 54.3%of the poisoned cases were in the age group1month-5year, compared to 37% and 8.6% of the age groups 6-10 and 11-12 yr respectively. Overall incidence of poisoning in males was much higher than females, but in the age group above 10 years there is increased incidence in females. Conclusion: outcome of poisoning is directly related to the interval between poisoning and presentation to emergency care. Immediate access to the medical management , responsible monitoring of the poisoned patients, rapid treatment and follow-ups are essential to improve the condition of these poisoned children.
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Background: Microscopists opine that acid-alcohol decolourized slides may enhance acid-fast bacilli (AFB) smear positivity, and published documents on equivalence of acid and acid-alcohol in ZN staining method are not easily accessible. Setting: National Institute for Research in Tuberculosis, Chennai, India. Objective: To document the equivalence of 25% sulphuric acid (ZN-acid method) and 3% hydrochloric acid-alcohol (ZNalcohol method) as decolourizing agents in ZN method for detection of acid-fast bacilli. Methods: Two smears from each of 253 sputum samples from pulmonary tuberculosis patients, prepared and allocated, one to ZN-acid method and another to ZN-alcohol method were read blind. All the specimens were cultured for Mycobacterium tuberculosis by modified Petroff’s method. Culture of M. tuberculosis was gold standard. Results: The concordance between the methods was 85% (kappa 0.68), and the sensitivity (79%) and specificity (89%) were same for both the methods. Conclusion: In conclusion, the common belief that acid-alcohol decolourized slides give enhanced smear positivity stands void.
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Aldol condensation between 1-oxo-1,2,3,4-tetrahydrocarbazole 1 and benzaldehyde yielded 2-benzylidine-1-oxo-1,2,3,4-tetrahydrocarbazole 2. Which on treatment with hydrazine hydrate in ethanol afforded substituted 4,5-dihydro-3-phenyl-2Hpyrazolo[ 3,4-a]carbazoles 3. The compound 2 on treatment with hydroxylamine hydrochloride in ethanol yielded 3-phenyl isooxazolo[3,4-a]carbazoles 4. Microwave irradiation of 2 with hydrazine hydrate and hydroxylamine hydrochloride in ethanol separately yielded the same products 3 and 4 respectively.
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Microwave assisted new aldol condensation reaction of 1-oxo-1,2,3,4- tetrahydrocarbazoles 1 with thiophene-2-carbaldehyde 2 in the presence of alcoholic KOH affords a single product 2-Thiophen-2-ylmethylene-2,3,4,9-tetrahydro-carbazol-1-one 3. 3 on irradiation with hydroxylamine hydrochloride yielded 3-Thiophen-2-yl-4,5-dihydro-10H-2-oxa-1,10-diazacyclopenta[ a]carbazole 4 and 3 on irradiation with hydrazine hydrate in ethanol medium to yielded 3-Thiophen-2-yl-2,4,5,10-tetrahydro-1,2,10-triaza-cyclopenta[a]carbazole 5. The structures of the synthesized compounds were confirmed on the basis of physical and spectral analysis (FT-IR, 1H, 13C-NMR) and Mass spectral data.
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Investigation was carried out on the diversity of butterfly fauna in selected localities of conservation and breeding center of Arignar Anna Zoological Park (AAZP), Chennai, Tamil Nadu. A total of 56 species were recorded, 15 of them belonged to Pieridae, 12 Nymphalidae, 9 Satyridae, 8 Papilionidae, 7 Danaidae, 3 Lycaenidae and 1 species each belonged to the families Acraeidae and Hesperidae. Qualitatively and quantitatively Pieridae family were comparatively dominant than that of other families. The notable addition to the 25 more species listed during this observation were compared to previous field survey. Comparison of butterfly species distribution between the different localities revealed that butterfly species richness was higher at mountain region with 52 species and lowest of 25 species at public visiting areas. Visitor’s activities may be that reason for effects on butterfly distribution and lack of vegetation. Each five endemic and protected species (i.e. endangered) listed under the Wildlife (Protection) Act were highlighted greater conservation importances of the AAZP. It is suggest that butterfly species diversity generally increase with increase in vegetation and declines with the increase in disturbance.
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Plankton diversity and physico-chemical parameters are an important criterion for evaluating the suitability of water for irrigation and drinking purposes. In this study, we tried to assess the zooplankton species richness, diversity, and evenness and to predict the state of three perennial ponds according to physico-chemical parameters. A total of 47 taxa were recorded: 24 rotifers, 9 copepods, 8 cladocerans, 4 ostracods and 2 protozoans. More number of zooplankton species were recorded in Chinnapperkovil pond (47 species) followed by Nallanchettipatti (39 species) and Kadabamkulam pond (24 species). Among the rotifers, Branchionus sp. is abundant. Diaphanosoma sp. predominant among the cladocerans. Among copepods, numerical superiority was found in the case of Mesocyclopes sp. Cypris sp. repeated abundance among ostracoda. Present study revealed that zooplankton species richness (R1 and R2) was comparatively higher (R1: 4.39; R2: 2.13) in Chinnapperkovil pond. The species diversity was higher in the Chinnapperkovil pond (H’: 2.53; N1: 15.05; N2: 15.75) as compared to other ponds. The water samples were analyzed for temperature, pH, electrical conductivity, alkalinity, salinity, phosphate, hardness, dissolved oxygen and biological oxygen demand. Higher value of physico-chemical parameters and zooplankton diversity were recorded in Chinnapperkovil pond as compared to other ponds. The zooplankton population shows positive significant correlation with physico-chemical parameters like, temperature, alkalinity, phosphate, hardness and biological oxygen demand, whereas negatively correlated with rainfall and salinity. The study revealed that the presence of certain species like, Monostyla sp., Keratella sp., Lapadella sp., Leydigia sp., Moinodaphnia sp., Diaptomus sp., Diaphanosoma sp., Mesocyclopes sp., Cypris sp. and Brachionus sp. is considered to be biological indicator for eutrophication.
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BACKGROUND & OBJECTIVES: Sensitivity of Ziehl-Neelsen (ZN) method is known to be low for liquefied sputum smears. Information on the ZN sensitivity for centrifuged deposit smears is not known. This study was carried out to determine the sensitivity of ZN method for acid fast bacilli (AFB) in centrifuged deposit smears and liquefied sputum smears made from sputum samples transported in cetyl-pyridinium chloride (CPC) solution. METHODS: Liquefied sputum smears and the corresponding centrifuged deposit smears from each of the 607 consecutive sputum samples collected from tuberculosis patients admitted to receive treatment transported in CPC were read by the same readers and their results compared with culture results. RESULTS: A significantly (P<0.001) higher proportion of samples were positive in centrifuged deposit smears (40%) compared to liquefied sputum smears (30%). The results of 341 culture-positive specimens revealed that the sensitivity of ZN method was 47 per cent using liquefied sputum smears and 63 per cent using centrifuged deposit smears (P<0.001). INTERPRETATION & CONCLUSION: Our study demonstrated that the sensitivity of ZN method for AFB in centrifuged deposit smears and liquefied sputum smears was reduced if sputum samples are transported in CPC solution.